Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1H)-one derivatives as potential MERS-CoV inhibitors
Identifieur interne : 000358 ( Main/Exploration ); précédent : 000357; suivant : 000359Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1H)-one derivatives as potential MERS-CoV inhibitors
Auteurs : Ji Hye Yoon [Corée du Sud] ; Jun Young Lee [Corée du Sud] ; Jihye Lee [Corée du Sud] ; Young Sup Shin [Corée du Sud] ; Sangeun Jeon [Corée du Sud] ; Dong Eon Kim [Corée du Sud] ; Jung Sun Min [Corée du Sud] ; Jong Hwan Song [Corée du Sud] ; Seungtaek Kim [Corée du Sud] ; Sunoh Kwon [Corée du Sud] ; Young-Hee Jin [Corée du Sud] ; Min Seong Jang [Corée du Sud] ; Hyoung Rae Kim [Corée du Sud] ; Chul Min Park [Corée du Sud]Source :
- Bioorganic & Medicinal Chemistry Letters [ 0960-894X ] ; 2019.
Abstract
Url:
DOI: 10.1016/j.bmcl.2019.126727
PubMed: 31624041
PubMed Central: 7126094
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1<italic>H</italic>)-one derivatives as potential MERS-CoV inhibitors</title><author><name sortKey="Yoon, Ji Hye" sort="Yoon, Ji Hye" uniqKey="Yoon J" first="Ji Hye" last="Yoon">Ji Hye Yoon</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Jun Young" sort="Lee, Jun Young" uniqKey="Lee J" first="Jun Young" last="Lee">Jun Young Lee</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Jihye" sort="Lee, Jihye" uniqKey="Lee J" first="Jihye" last="Lee">Jihye Lee</name><affiliation wicri:level="1"><nlm:aff id="af010">Respiratory Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Respiratory Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 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34114</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Seungtaek" sort="Kim, Seungtaek" uniqKey="Kim S" first="Seungtaek" last="Kim">Seungtaek Kim</name><affiliation wicri:level="1"><nlm:aff id="af020">Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488</wicri:regionArea><wicri:noRegion>Gyeonggi-do 13488</wicri:noRegion></affiliation></author><author><name sortKey="Kwon, Sunoh" sort="Kwon, Sunoh" uniqKey="Kwon S" first="Sunoh" last="Kwon">Sunoh Kwon</name><affiliation wicri:level="1"><nlm:aff id="af015">Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 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Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Jun Young" sort="Lee, Jun Young" uniqKey="Lee J" first="Jun Young" last="Lee">Jun Young Lee</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Jihye" sort="Lee, Jihye" uniqKey="Lee J" first="Jihye" last="Lee">Jihye Lee</name><affiliation wicri:level="1"><nlm:aff id="af010">Respiratory Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Respiratory Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488</wicri:regionArea><wicri:noRegion>Gyeonggi-do 13488</wicri:noRegion></affiliation></author><author><name sortKey="Shin, Young Sup" sort="Shin, Young Sup" uniqKey="Shin Y" first="Young Sup" last="Shin">Young Sup Shin</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Jeon, Sangeun" sort="Jeon, Sangeun" uniqKey="Jeon S" first="Sangeun" last="Jeon">Sangeun Jeon</name><affiliation wicri:level="1"><nlm:aff id="af010">Respiratory Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Respiratory Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488</wicri:regionArea><wicri:noRegion>Gyeonggi-do 13488</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Dong Eon" sort="Kim, Dong Eon" uniqKey="Kim D" first="Dong Eon" last="Kim">Dong Eon Kim</name><affiliation wicri:level="1"><nlm:aff id="af015">Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054</wicri:regionArea><wicri:noRegion>Daejeon 34054</wicri:noRegion></affiliation></author><author><name sortKey="Min, Jung Sun" sort="Min, Jung Sun" uniqKey="Min J" first="Jung Sun" last="Min">Jung Sun Min</name><affiliation wicri:level="1"><nlm:aff id="af015">Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054</wicri:regionArea><wicri:noRegion>Daejeon 34054</wicri:noRegion></affiliation></author><author><name sortKey="Song, Jong Hwan" sort="Song, Jong Hwan" uniqKey="Song J" first="Jong Hwan" last="Song">Jong Hwan Song</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Seungtaek" sort="Kim, Seungtaek" uniqKey="Kim S" first="Seungtaek" last="Kim">Seungtaek Kim</name><affiliation wicri:level="1"><nlm:aff id="af020">Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do 13488</wicri:regionArea><wicri:noRegion>Gyeonggi-do 13488</wicri:noRegion></affiliation></author><author><name sortKey="Kwon, Sunoh" sort="Kwon, Sunoh" uniqKey="Kwon S" first="Sunoh" last="Kwon">Sunoh Kwon</name><affiliation wicri:level="1"><nlm:aff id="af015">Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054</wicri:regionArea><wicri:noRegion>Daejeon 34054</wicri:noRegion></affiliation></author><author><name sortKey="Jin, Young Hee" sort="Jin, Young Hee" uniqKey="Jin Y" first="Young-Hee" last="Jin">Young-Hee Jin</name><affiliation wicri:level="1"><nlm:aff id="af015">Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054</wicri:regionArea><wicri:noRegion>Daejeon 34054</wicri:noRegion></affiliation></author><author><name sortKey="Jang, Min Seong" sort="Jang, Min Seong" uniqKey="Jang M" first="Min Seong" last="Jang">Min Seong Jang</name><affiliation wicri:level="1"><nlm:aff id="af025">Department of Non-Clinical Studies, Korea Institute of Toxicology, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Non-Clinical Studies, Korea Institute of Toxicology, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Hyoung Rae" sort="Kim, Hyoung Rae" uniqKey="Kim H" first="Hyoung Rae" last="Kim">Hyoung Rae Kim</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author><author><name sortKey="Park, Chul Min" sort="Park, Chul Min" uniqKey="Park C" first="Chul Min" last="Park">Chul Min Park</name><affiliation wicri:level="1"><nlm:aff id="af005">Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114</wicri:regionArea><wicri:noRegion>Daejeon 34114</wicri:noRegion></affiliation></author></analytic><series><title level="j">Bioorganic & Medicinal Chemistry Letters</title><idno type="ISSN">0960-894X</idno><idno type="eISSN">1464-3405</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Graphical abstract</title><fig 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Lee</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Corée du Sud</li></country></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Yoon, Ji Hye" sort="Yoon, Ji Hye" uniqKey="Yoon J" first="Ji Hye" last="Yoon">Ji Hye Yoon</name></noRegion><name sortKey="Jang, Min Seong" sort="Jang, Min Seong" uniqKey="Jang M" first="Min Seong" last="Jang">Min Seong Jang</name><name sortKey="Jeon, Sangeun" sort="Jeon, Sangeun" uniqKey="Jeon S" first="Sangeun" last="Jeon">Sangeun Jeon</name><name sortKey="Jin, Young Hee" sort="Jin, Young Hee" uniqKey="Jin Y" first="Young-Hee" last="Jin">Young-Hee Jin</name><name sortKey="Kim, Dong Eon" sort="Kim, Dong Eon" uniqKey="Kim D" first="Dong Eon" last="Kim">Dong Eon Kim</name><name sortKey="Kim, Hyoung Rae" sort="Kim, Hyoung Rae" uniqKey="Kim H" first="Hyoung Rae" last="Kim">Hyoung Rae Kim</name><name sortKey="Kim, Seungtaek" sort="Kim, Seungtaek" uniqKey="Kim S" first="Seungtaek" last="Kim">Seungtaek Kim</name><name sortKey="Kwon, Sunoh" sort="Kwon, Sunoh" uniqKey="Kwon S" first="Sunoh" last="Kwon">Sunoh Kwon</name><name sortKey="Lee, Jihye" sort="Lee, Jihye" uniqKey="Lee J" first="Jihye" last="Lee">Jihye Lee</name><name sortKey="Lee, Jun Young" sort="Lee, Jun Young" uniqKey="Lee J" first="Jun Young" last="Lee">Jun Young Lee</name><name sortKey="Min, Jung Sun" sort="Min, Jung Sun" uniqKey="Min J" first="Jung Sun" last="Min">Jung Sun Min</name><name sortKey="Park, Chul Min" sort="Park, Chul Min" uniqKey="Park C" first="Chul Min" last="Park">Chul Min Park</name><name sortKey="Shin, Young Sup" sort="Shin, Young Sup" uniqKey="Shin Y" first="Young Sup" last="Shin">Young Sup Shin</name><name sortKey="Song, Jong Hwan" sort="Song, Jong Hwan" uniqKey="Song J" first="Jong Hwan" last="Song">Jong Hwan Song</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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